{"id":2751,"date":"2022-11-28T05:38:54","date_gmt":"2022-11-28T05:38:54","guid":{"rendered":"\/?page_id=2751"},"modified":"2022-11-28T05:45:52","modified_gmt":"2022-11-28T05:45:52","slug":"technology-key-features-of-the-sparx-bifunctional-adc-technology","status":"publish","type":"page","link":"\/?page_id=2751","title":{"rendered":"Technology: Key features of the Sparx Bifunctional ADC technology"},"content":{"rendered":"\n<ul>\n<li>Proprietary cutting-edge multi-specific antibody strategies to ensure exquisite specificity and optimal internalization<\/li>\n\n\n\n<li>Homogenous glycosylation profile enabled by proprietary NECOR<sup>TM<\/sup> technology<\/li>\n\n\n\n<li>Flexible site-specific conjugation schema powered by NECOR<sup> TM<\/sup> and site-specific mutations<\/li>\n\n\n\n<li>Homogenous ADCs with customized DARs (drug-to-antibody ratio) of 2, 4, 6, or 8<\/li>\n\n\n\n<li>Protease or caspase-dependent peptide linkers to increase tumor accumulation and bystander effect<\/li>\n\n\n\n<li>Consistency in product&nbsp; from pilot to&nbsp; manufacturing scale<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":2389,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"page-fullwidth.php","meta":[],"_links":{"self":[{"href":"\/index.php?rest_route=\/wp\/v2\/pages\/2751"}],"collection":[{"href":"\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2751"}],"version-history":[{"count":1,"href":"\/index.php?rest_route=\/wp\/v2\/pages\/2751\/revisions"}],"predecessor-version":[{"id":2752,"href":"\/index.php?rest_route=\/wp\/v2\/pages\/2751\/revisions\/2752"}],"up":[{"embeddable":true,"href":"\/index.php?rest_route=\/wp\/v2\/pages\/2389"}],"wp:attachment":[{"href":"\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2751"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}